Expedition 75 is midway through a crew swap aboard the International Space Station, NASA reported on Oct. 5, 2026. The station's 11 crew members have been packing and unpacking the two SpaceX Dragon spacecraft docked at the Harmony module while preparing for upcoming cargo activities.

New Expedition 75 members Jessica Watkins and Luke Delaney of NASA, Josh Kutryk of the Canadian Space Agency and Sergey Teteryatnikov of Roscosmos have lived and worked on the station since Thursday, Oct. 1. They launched as NASA's SpaceX Crew-13, docking at Harmony's forward port the same day, and are beginning a six-month research mission. Meanwhile, the Crew-12 quartet, aboard since Feb. 14, was reported as scheduled to depart at 8:05 a.m. EDT on Wednesday, Oct. 7, with NASA astronauts Jessica Meir and Jack Hathaway commanding and piloting Dragon alongside mission specialists Sophie Adenot of ESA and Andrey Fedyaev of Roscosmos. The plan called for undocking from Harmony's space-facing port and a Pacific splashdown at 11:34 a.m. on Thursday, Oct. 8, ending a stay of nearly eight months.

Roscosmos cosmonaut Pyotr Dubrov accepted station command from Meir during a traditional ceremony on Sunday, Oct. 4. He will remain in space with flight engineers Anna Kikina of Roscosmos and Anil Menon of NASA until spring 2027. Northrop Grumman's uncrewed Cygnus XL resupply ship, attached to the Unity module since April 13, was reported as scheduled for release by the Canadarm2 robotic arm at the end of the week, ahead of SpaceX's 35th commercial resupply mission.