Police announced on October 6 that crowd safety management measures and special traffic arrangements will be implemented in Kowloon and the New Territories on October 10 and 11 for the Hong Kong Cyclothon. Roads within the closure areas will be shut to all vehicular traffic except vehicles holding closed road permits issued by the Transport Department.

In Kowloon, closures begin with a layby and slow lane on Mody Road westbound from noon on October 10 to about 6pm on October 11. Further phases on October 11 affect sections of West Kowloon Highway, Nga Cheung Road, Jordan Road, Lin Cheung Road and the Central Kowloon Bypass, with diversions via routes including Lai Cheung Road, Lung Cheung Road and Chatham Road North. In the New Territories, closures on October 11 cover the upper deck of the Lantau Link Kowloon bound, the Eagle's Nest and Sha Tin Heights tunnels Sha Tin bound, and parts of Tsing Kwai Highway, Ting Kau Bridge and Tsing Sha Highway, with temporary speed limits on several highways.

Green minibus stands, taxi stands and pick-up points, loading bays and on-street parking spaces in West Kowloon closure areas will be suspended in phases from 1am on October 11. Access to car parks in affected areas will be barred during closures. Access to the West Kowloon Cultural District, Kowloon Station and Hong Kong West Kowloon Station will be diverted during specified periods. Traffic on both bounds of the Western Harbour Crossing is expected to remain normal.