NASA described biomedical and human performance studies planned for the SpaceX Crew-13 mission aboard the International Space Station in a report published Sept. 24, 2026. Among them is Venous Haemostasis, a new collaboration with ESA that combines the agencies' blood-flow research. By coordinating blood collections and physiological data, investigators aim to reduce the frequency of astronauts' blood draws while better understanding how microgravity affects clotting and circulation. Crew members were to undergo MRI scans, jugular vein ultrasounds, blood pressure checks and blood draws before, during and after flight.

A Manual Piloting study was to use lunar-landing simulations to assess astronauts' handling of challenging landings after extended time in microgravity, and whether refresher training shortly before landing helps. Researchers also planned to continue the B-Complex study, testing whether a daily B-vitamin supplement can reduce or prevent Spaceflight-Associated Neuro-ocular Syndrome, with vision tests and supplements before, during and after flight.

Select astronauts were also slated for three Human Research Program studies: Standard Measures, collecting physiological and behavioral baselines; Spacecraft Occupant Risk, characterizing landing forces to refine hardware and strategies; and Zero T2, comparing crew members who use the station treadmill with those who do not to inform exercise plans for future Artemis and deep-space missions.