A NASA report published September 21, 2026, described Expedition 75 crew activities aboard the International Space Station that Monday, covering human research, cargo transfers and Earth observation equipment. NASA astronauts Jessica Meir and Jack Hathaway took body measurements with a tape measure in the Columbus laboratory module and entered results in the EveryWear app for ground analysis, work NASA said would help researchers understand how weightlessness affects astronauts' height and circumference.

Meir and NASA flight engineer Anil Menon moved cargo in and out of the Cygnus XL spacecraft, berthed to the Unity module's Earth-facing port since April 13, and packed items slated to return on SpaceX Dragon when Crew-12 ends its mission the following month. NASA said the next Dragon was targeted to arrive with the Crew-13 launch as soon as early October. ESA's Sophie Adenot began her shift setting up a motion capture system for exercise research on the Tranquility module's advanced resistive exercise device.

Roscosmos flight engineers Pyotr Dubrov and Anna Kikina unpacked Progress 96, which docked to the Poisk module the previous Saturday carrying nearly three tons of food, fuel and supplies, NASA said, and took turns wearing an acoustic monitor recording rapid exhalation rate. Andrey Fedyaev tested a lower body negative pressure suit with Kikina's assistance and later activated automated Earth-imaging gear to capture imagery of Asia, the Pacific Ocean and North America during the crew's sleep shift.