Expedition 75 began the week with vein scans, checks of space workout equipment and tests of specialized suits intended to ease the adjustment to Earth's gravity, NASA reported on Sept. 28, 2026. On Earth, the NASA SpaceX Crew-13 members were counting down to a launch planned for Oct. 1.

NASA astronauts Jessica Meir and Anil Menon started their shift with vein scans in the Columbus laboratory module. Meir used the Ultrasound 3 device to scan Menon's jugular vein and measured his blood pressure for the Venous Flow investigation, which doctors will use to look for potential space-caused blood conditions. Jack Hathaway collected a blood sample for a red blood cell count. Later, Meir joined the three crewmates she is set to return to Earth with next week to test specialized suits that may help them adjust after nearly eight months in space.

Sophie Adenot of ESA tested exercise-research hardware and guided Menon on the European Enhanced Exploration Exercise Device. Andrey Fedyaev conducted a session with a Roscosmos-designed lower body negative pressure suit. Pyotr Dubrov explored high-purity semiconductor crystals in the Nauka science module.